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Root Causes of Low Vaccination Coverage and Under-Immunisation in Sub-Saharan Africa

dc.contributor.authorAcademy of Science of South Africa (ASSAf)
dc.identifier.citationAcademy of Science of South Africa (ASSAf), (2021). Root Causes of Low Vaccination Coverage and Under-Immunisation in Sub-Saharan Africa.[Available online:] DOI:
dc.descriptionAcademy of Science of South Africa (ASSAf), (2021). Root Causes of Low Vaccination Coverage and Under-Immunisation in Sub-Saharan Africa.en_ZA
dc.description.abstractSub–Saharan Africa (SSA) alone accounts for 40% of all global deaths, a phenomenon attributed to lack of access to available lifesaving vaccines (Wiysonge, Uthman, Ndumbe, & Hussey, 2012). WHO estimates that in 2019 the African region accounted for approximately 43% of unimmunised and incomplete immunised infants in the world (i.e.: 8.5 million of the global 19.4 million). Relatedly, the region scores the lowest immunisation coverage, at 76% versus the global coverage of 86% (WHO, 2020a). This is despite several documented efforts by different stakeholders to improve coverage in the region (Mihigo, Okeibunor, Anya, Mkanda, & Zawaira, 2017). Many studies have been conducted on coverage and drivers for and bottlenecks against immunisation in SSA. (Wiysonge, Uthman, Ndumbe, & Hussey, 2012), (Wiysonge, Young, Kredo, McCaul, & Volmik, 2015), (Mihigo, Okeibunor, Anya, Mkanda, & Zawaira, 2017), (Madhi & Rees, 2018),(Bangura, et al., 2020), all of which have observed that there is varied performance among the constituent countries, and also within countries over time, denoting some implicitly common underlying correlates threading through areas of higher performance; and the same is seen with the poorer performing areas. This consensus study therefore seeks to categorise and make explicit these “root causes” and based on documented successes, to make recommendations to address the bottlenecks and harness the opportunities for reaching every child with all the recommended vaccines. The theory of change presentation style used in this report, categorising the root causes under four broad interlinked themes, can provide a common basis to rally like-minded partners around a thematic cause and thus develop multi-component, comprehensive strategies to bring about impactful change. This is in line with the call made by the World Health Organisation Strategic Advisory Group of Experts on Immunisation, which recommended that countries, regions and global immunisation partners commit to a comprehensive review of progress, impact, and implementation of the WHO Global Vaccine Action Plan to inform a post-2020 strategy taking into account lessons learned. This strategy will assist with attaining the relevant United Nations Sustainable Development Goals by 2030.en_ZA
dc.description.sponsorshipDepartment of Science and Innovation (DSI) South African Medical Research Council (SAMRC)en_ZA
dc.publisherAcademy of Science of South Africa (ASSAf)en_ZA
dc.subjectLow Vaccinationen_ZA
dc.subjectSub-Saharan Africaen_ZA
dc.titleRoot Causes of Low Vaccination Coverage and Under-Immunisation in Sub-Saharan Africaen_ZA
dc.typeConsensus Study Reporten_ZA

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  • A. ASSAf Consensus Study Reports45

    Consensus Study Reports are either commissioned by an external funder or generated by a Standing Committee on a specific topic.

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